UCR

Molecular, Cell and Systems Biology



Positions


Open Faculty Positions

 

Assistant/Associate Professor in Metabolomics of Adaptive Responses

The University of California, Riverside (UCR) invites applications for tenure-track faculty positions at the Assistant or Associate level in the area of metabolomics focusing on cellular and physiological responses. These positions are part of a major initiative in the area of metabolomics, as UCR seeks to hire five faculty in this research area in the next three years. The new faculty will build on UCR’s current strengths in: infectious disease; host-pathogen interactions; environmental toxicology; neuroscience, aging and neurodegeneration; stem cells in development and tissue repair; evolution of secondary metabolic pathways; medicinal plants; plant secondary metabolites and human health; as well as emerging research areas such as microbiomes, eco-metabolomics, and quantitative metabolomic imaging and downstream analyses.

Successful candidates will have an appointment in an appropriate department in the College of Natural and Agricultural Sciences, School of Medicine, or Bourns College of Engineering where researchers are already working on the metabolomics of cellular signaling including chronic diseases (cardiovascular, gastrointestinal and metabolic), nutrition, mathematical and computational modeling, plant biology, and agriculture.

Successful candidates must possess an M.D. or Ph.D. degree and postdoctoral experience is preferred.  Candidates must demonstrate notable scientific contributions, evidenced by high quality peer-reviewed publications. Assistant-level applicants will be expected to set up an independent research program and must demonstrate the potential to secure extramural funding. Associate-level applicants are expected to have established research programs and a strong record of sustained extramural funding. All candidates should be able to demonstrate cutting-edge expertise in the development or application of metabolomics, including imaging, to biological signaling.

The University of California, Riverside is ranked among the nation’s Top 15 Public Research Universities according to Washington Monthly. The successful candidate will have access to the state-of-the-art facilities in cores operated by the Institute of Integrative Genome Biology (IIGB), which includes the recently launched Metabolomics Core, as well as cores dedicated to bioinformatics, microscopy, proteomics, and sequencing. Faculty are encouraged to collaborate broadly with colleagues at UCR and elsewhere, and entrepreneurship is encouraged.

As a world-class research university with an exceptionally diverse undergraduate student body, UCR’s mission is explicitly linked to providing routes to educational success for underrepresented and first-generation college students. A commitment to this mission is a preferred qualification.

Salary will be competitive and commensurate with qualifications and experience.  A competitive start-up package will be provided. Advancement through the faculty ranks at the University of California is through a series of structured, merit-based evaluations, occurring every two to three years, each of which includes substantial peer input.

UCR is centrally located within the Southern California area and situated in a historic citrus-growing area surrounded by mountain ranges. Riverside is an hour away from ski slopes, surfing, or hiking in mountain wilderness or desert environments, and housing in the area is affordable. The campus boasts a fully-accredited child care facility. UCR maintains a commitment to “family friendly” policies and programs including opportunities for spousal/partner hiring. UCR is located in close proximity to a host of high-profile universities, research institutes, and biotech industries in Southern California.

To apply:

Applicants for the Assistant Professor level position should apply through: https://aprecruit.ucr.edu/apply/JPF01090. Applicants for the Associate Professor level should apply through: https://aprecruit.ucr.edu/apply/JPF01091.  If a candidate has a pending tenure decision at their current institution, applying for both the Assistant and Associate level positions is encouraged to allow hiring at the appropriate level within the University of California. Minorities and members of underrepresented groups are particularly encouraged to apply.

Applicants should submit a Cover Letter, Curriculum Vitae, Publication List, Statement of Research, Teaching Philosophy Statement, and a Contributions to Diversity Statement at the site(s) above. Names of three to five individuals for Letters of Reference should be submitted to the site(s) above; letter requests will occur immediately for applicants for the Assistant level position. Letters will be requested for applications at the Associate level after application material review. All confidential Letters of Recommendation will be uploaded to the recruitment website.

Review of applications will begin on June 1, 2019. We will continue to consider applications until the position is filled. For full consideration, applicants should submit their complete applications and have all Letters of Reference arrive by the above date.  The position will remain open until filled.

Additional inquiries regarding the position should be directed to Dr. Linda Walling, Search Committee Chair (email: lwalling@ucr.edu). For inquiries regarding the application process, please contact Eric Chong, Academic Personnel (eric.chong@ucr.edu).

Open Postdoctoral Positions

 

POSTDOCTORAL POSITIONS IN NEURAL CIRCUITS

Several postdoctoral positions are available immediately for highly-motivated individuals interested in understanding the mechanisms underlying neural circuit function and development. The individuals will join one of multiple laboratories at the University of California, Riverside interested in 1) neuromodulation of perception and decision making, 2) brain circuit development, or 3) hormonal regulation of innate behavior.

Who you are:

·         A PhD or MD-PhD degree in neuroscience or related disciplines

·         Excellent communication skills

·         A demonstrated ability to work independently and learn new techniques

·         Candidates with less than 3 years of postdoctoral training are preferred

Who we are:

-     The Yang Lab: Our lab employs electrophysiology, calcium imaging, optogenetics and quantitative behavior approaches to understand the cellular and circuit mechanisms underlying neuromodulatory regulation of sensory processing and decision-making in mice. Solid experience in in vivo electrophysiology, or in vivo calcium imaging is required. Analytical skills with Matlab or Python is a plus. For more information, please visit https://www.hyanglab.com/positions. Send materials to: hongdian@ucr.edu.

-     The Riccomagno Lab: Our laboratory uses a combination of molecular biology, histology, and cutting-edge imaging and mouse transgenic approaches to investigate the developmental mechanisms that regulate neural circuit formation. Proficiency in cellular and molecular biology is a must. Previous experience in mouse genetics is preferred. For more information, please visit http://www.riccomagnolab.org. Send materials to: martinmr@ucr.edu

-     The Haga-Yamanaka Lab: Our laboratory utilizes molecular biology, cell biology, histology, behavior study, mouse genetics, as well as omics approaches to investigate innate behavioral circuits regulated by steroid hormone signaling in mice. Strong cellular and molecular biology background is required. Previous experience in mouse behavior study is preferred. For more information, please visit https://cbns.ucr.edu/faculty/haga-yamanaka.html.  Send materials to: sachikoy@ucr.edu

To Apply:  Interested applicants should submit a cover letter, CV and contact information for 3 references.  Positions are open until filled. 

 

POSTDOCTORAL SCHOLARS IN OXIDATIVE STRESS AND DISEASE 

The laboratory of Dr. Manuela Martins-Green in the Department of Molecular, Cell, and Systems Biology at the University of California, Riverside is looking for two highly motivated postdoctoral scholars to join its research team working on cell and molecular mechanisms of response to injury. 

Position one: The research will focus on determining whether injury caused by toxins, specifically third-hand smoke (THS) toxins, lead to epigenetic changes that result in reduced production of ATP. We also seek to determine whether those changes are passed on from generation to generation and for how long they might remain. This project will also involve other basic mechanisms of mitochondrial function affected by exposure to THS.  For these studies we have developed a novel exposure system of mice that mimics exposure of children to THS in homes of smokers.  The results we will obtain will have implications for policy changes to reduce/avoid exposure of children, elderly and those who live with smokers.

Position two: The research will focus with on basic cell and molecular mechanisms of initiation of chronic wound development.  We will be investigating how high levels of Oxidative Stress (OS) lead to changes in the genome, microbiome, proteome and metabolome that put the wound on a path to chronicity.  For these studies we have developed a novel chronic wound model in diabetic mice (db/db-/-) which we have shown mimics chronic wounds in humans. When we raise the levels of OS right after wounding the wound goes on to become chronic with biofilm that contains biofilm-forming bacteria that are found in human chronic wounds.  We are now in a position to determine how high levels of OS put the wound on a path to chronicity.  The results we will obtain may lead to studies of proof-of-concept in humans with chronic wounds that could then lead to the development of new therapies for chronicity.

Qualifications for both positions: Applicants should hold a Ph.D. degree in Biological Sciences with an emphasis in cell and molecular biology and associated technology. Previous experience with metabolomics, proteomics, transcriptomics or bioinformatics would be helpful. Strong communication skills (both written and spoken) are required. Candidates should be able to work both independently and in a collaborative environment.

Salary:  Candidates will be offered a competitive salary commensurate with their experience

Individuals interested in applying should send their curriculum vitae (CV), a description of their research experience, a statement of research interests, and a list of three references via email to: manuela.martins@ucr.edu.

Dr. Weifeng Gu’s lab, located in the Department of Molecular, Cell and Systems Biology at UC Riverside, focuses on small noncoding RNA/RNAi-mediated gene regulation and antiviral response. We are looking for a highly motivated postdoc to examine how a highly conserved RNA phosphatase regulates genes and RNA viruses in C. elegans and other systems. This research involves RNA biogenesis, antivirus, gene regulation, innate immunity, developmental biology, genomics, RNAi, bioinformatics and cell biology.

The candidate is expected to have extensive knowledge and skills in RNA biology, biochemistry and genetics, with skills in bioinformatics and worm genetics as a plus. This position is funded by NIH and will support a postdoc for 4-5 years with a competitive salary and benefits.  UCR is a great place for working and living.

To Apply:  Please send a CV and a brief cover letter to Dr. Weifeng Gu at weifeng.gu@ucr.edu.

 

MOLECULAR TOXICOLOGY - available immediately

NIH-funded postdoctoral positions are now available in Sarjeet Gill’s laboratory at the Department of Cell Biology and Neuroscience, University of California, Riverside. The lab investigates the mechanism of action of mosquitocidal active bacterial proteins.  The current focus is in the expression of a novel bacterial toxin isolated from Clostridium and characterization its mechanisms.  Other projects involve elucidation of mechanisms of insect tolerance or resistance to mosquitocidal toxins derived from Bacillus thuringiensis israelensis. 

Applicants should have significant experience in biochemistry, molecular biology and microbiology.  Candidates should have a recent PhD in a biological science, and have a record of research productivity.   Applicants must be able to work in a group environment and be results-oriented.

To apply please send a cover letter describing research interests and goals, a detailed curriculum vitae and contact information for three references to Sarjeet Gill, Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521 (sarjeet.gill@ucr.edu).  The positions are available beginning July 1 2016 but review of application will begin immediately.

 

Developmental Biology and Environmental Toxicology

Two postdoctoral positions are available in the zur Nieden lab at the University of California Riverside to study how microRNAs tune early skeletal development. We have previously identified a powerful microRNA that enhances osteogenesis in vitro and now aim to analyze its role and that of its direct target in vivo using knockout and knock-in mice and genetic manipulation of Xenopus embryos. Similarly, we are interested in identifying how this and other microRNAs act to induce skeletal birth defects when embryos are exposed to environmental toxicants in utero.

The laboratory uses a combination of cellular (human ESCs, iPSCs, neural crest cells), molecular and genetic tools to understand how these microRNAs tune early differentiation - primarily that of the neural crest - to lay the foundation for proper craniofacial osteogenesis. For an overview of this and other projects in the lab please see our recent publications and the lab’s web page http://zurniedenlab.wix.com/ucrzurniedenlab.

Applications are invited from outstanding applicants with interests in neural crest, mesodermal or skeletal development and/or with an interest in stem cell biology and toxicology. Applicants are expected to work closely with collaborators Dr. Martin Garcia-Castro (University of California Riverside) and Dr. Bruce Blumberg (University of California Irvine) and in a team together with Graduate and undergraduate students.

Applicants should have a Ph.D and less than four years of postdoctoral experience. Knowledge in mouse breeding and husbandry, human embryonic stem cell culture and next generation sequencing is desirable. To apply send a curriculum vitae, bibliography and a cover letter with a brief description of research experience and the names of 3 references (with phone numbers) via e-mail to nicole.zurnieden@ucr.edu.

Open Project Scientist Positions

The Yang Lab at the University of California, Riverside is seeking talented, highly motivated candidates to fill 2 junior specialist positions. Our lab is uniquely positioned to combine state-of-the-art recording and manipulation techniques with computational modeling to address important questions in systems neuroscience.

Our current research is focused on the functions of subcortical neuromodulatory circuits. We employ multi-disciplinary approaches, including in vivo patch-clamp and multi-channel electrophysiology, calcium imaging, optogenetics, chemogenetics, quantitative animal behavior and computational modeling (e.g. Yang, Kwon, Severson, O’Connor, Nature Neuroscience 2016; Kwon, Yang, Minamisawa, O’Connor, Nature Neuroscience 2016; Yang, Shew, Roy, Plenz, Journal of Neuroscience 2012) to understand the cellular and circuit mechanisms underlying neuromodulatory regulation of sensory processing and decision-making in mice.

Position purpose

Under supervision, assist PI with research in the field of systems neuroscience.

Essential job functions

-Organize and keep laboratory mouse colony

-Assist with experiments for laboratory using a variety of behavioral, electrophysiological, and imaging approaches

-Dissect mouse tissue and prepare it for histology

-Assist in data collection

-Assist in the assembly, testing and operation of complex laboratory equipment

Minimum requirements

-Bachelor’s degree

-Comfortable handling mice

-Experience of basic rodent behavior

-Knowledge of use of routine lab equipment

-College-level coursework including courses in the life sciences and/or demonstrated lab experience

Preferred qualifications

-Experience in histology

-Experience in electrophysiology or calcium imaging

-Bachelor’s degree in biology or related field

How to apply:

Interested applicants should submit a single PDF including a cover letter, CV and transcript to hongdian@ucr.edu. For additional information, please visit www.hyanglab.com.

The University of California is an Equal Opportunity/Affirmative Action Employer with a strong institutional commitment to the achievement of excellence and diversity among its faculty and staff. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, or any other characteristic protected by law.

UCR is a world-class research university with an exceptionally diverse undergraduate student body. Its mission is explicitly linked to providing routes to educational success for underrepresented and first-generation college students. A commitment to this mission is a preferred qualification.

Open Assistant Project Positions


More Information

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

Career OpportunitiesUCR Libraries
Campus StatusDirections to UCR

Department Information

Molecular, Cell and Systems Biology
2111 Biological Sciences Bldg.

Manuela Martins-Green: Chair of Molecular, Cell and Systems Biology
Tel: (951) 827-2831
Fax: (951) 827-3087
E-mail: manuela.martins@ucr.edu

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