Researchers at the University of California, Riverside, have completed a cross-sectional human study that compares biomarkers and metal concentrations in the urine of e-cigarette users, nonsmokers, and cigarette smokers. They found that the biomarkers, which reflect exposure, effect, and potential harm, are both elevated in e-cigarette users compared to the other groups and linked to...
Scientists have made a major breakthrough in understanding how the parasite that causes malaria is able to multiply at such an alarming rate, which could be a vital clue in discovering how it has evolved and how it can be stopped. For the first time, scientists have shown how certain molecules play an essential role...
New UC Riverside research shows soybean oil not only leads to obesity and diabetes, but could also affect neurological conditions like autism, Alzheimer’s disease, anxiety, and depression. Used for fast food frying, added to packaged foods, and fed to livestock, soybean oil is by far the most widely produced and consumed edible oil in the...
A biochemist at the University of California, Riverside, has received a grant from the Congressionally Directed Medical Research Programs, or CDMRP, of the U.S. Department of Defense to develop a novel lead compound to treat breast cancer, the second most commonly diagnosed cancer among American women. John Jefferson Perry, an assistant professor of biochemistry, is...
Comparative 3D genome organization in apicomplexan parasites Significance From yeast to human cells, genome organization in eukaryotes has a tight relationship with gene expression. We investigated the 3D organization of chromosomes in malaria parasites to identify possible connections between genome architecture and pathogenicity. Genome organization was dominated by the clustering of Plasmodium-specific gene families in...
An international research team led by scientists at the University of California, Riverside, and the La Jolla Institute for Immunology has found that malaria parasite genomes are shaped by parasite-specific gene families, and that this genome organization strongly correlates with the parasite’s virulence. The findings highlight the importance of spatial genome organization in gene regulation...
